Does COPD plus COVID-19 equal higher mortality?

Expert Name
Dr Jacob Schwartz

The evaluation of chronic obstructive pulmonary disease (COPD) patients with COVID-19 did not find increased mortality, nor a negative impact of exacerbation status. Similar results were found for asthma and COVID-19. “We sought to assess whether COPD or asthma are risk factors for intubation in COVID-19, as well as mortality in COVID-19,” Dr Jacob Schwartz (Lenox Hill Hospital, NY, USA)…

Treatable Traits in Chronic Inflammatory Airway Disease: Back to Basics

Expert Name
Prof. Zuzana Diamant

Introduction Over the past two centuries, there has been a gradual paradigm change in the way we look at chronic inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), shifting away from prototypic, organ-centred disease labels, coined by William Osler at the end of the 19th century, to differentiated disease subsets [1]. During the second half of the…

Benralizumab does not ameliorate COPD exacerbations

Expert Name
Prof. Gerard Criner

New research shows that the asthma drug benralizumab did not statistically decrease annual COPD exacerbation rates for patients with moderate to very severe COPD, a history of frequent moderate and/or severe exacerbations, and eosinophilic inflammation; although the team did report numeric decreases (GALATHEA/TERRANOVA trials). The data were published in the New England Journal of Medicine in conjunction with Prof. Gerard…