1-Minute Summary: Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline

Expert Name
Prof. Fernando Holguin

In 2014, the first guidelines for the treatment of severe asthma in children and adults were composed by the European Respiratory Society/American Thoracic Society (ERS/ATS) [1]. Since 2017, a multidisciplinary Task Force of asthma experts, co-chaired by Dr Fernando Holguin and Dr Andy Bush, has worked on an updated version. The Task Force made 6 recommendations that were not addressed…

Afbeelding met schermafbeelding Automatisch gegenereerde beschrijving

1-Minute Summary: EUFOREA Consensus on Biologics for CRSwNP with or without Asthma

Expert Name
Dr. Wytske Fokkens

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition of the sinonasal cavities [1-3]. It is frequently comorbid with asthma and both diseases share common underlying pathophysiological mechanisms driving the disease, including type 2 inflammation [3-9]. CRSwNP severely impacts quality of life and has a significant burden on society [10-12]. When symptoms are persistent or when there is…

1-Minute Summary: Biomarkers in asthma management: Time to move forward

Expert Name
Prof. Kjell Alving

Alving K, Diamant Z, Lucas S, et al. Point‐of‐care biomarkers in asthma management: Time to move forward Allergy. Allergy. 2020;75(4):995‐997. The Global Initiative for Asthma (GINA) report has directed clinical guidelines for asthma since 2014. Evidence comes from randomised controlled trials, but not from real-world or observational studies, which could be a limitation [1]. Asthma is a heterogeneous condition with…

Holistic View on Asthma

Expert Name
Prof. Zuzana Diamant

In the past 15 years, striking progress has been made in our understanding of the mechanisms underlying chronic inflammatory airway disease as well as the predisposing and interfering factors. These insights have resulted in a more holistic and personalised approach to the diagnosis and management of chronic inflammatory airway diseases including their comorbidities. At the annual congress of the European…

Dupilumab improves outcomes in chronic rhinosinusitis with nasal polyps and asthma

Expert Name
Dr Jorge Maspero

In a pooled analysis of the SINUS-24 and SINUS-52 trials, dupilumab significantly improved both upper and lower airway outcomes compared with placebo in patients with severe chronic rhinosinusitis with nasal polyps and comorbid asthma [1]. Dr Jorge Maspero (Fundación CIDEA, Argentina) presented the research in a late-breaking clinical trial session, pointing out that asthma and chronic rhinosinusitis with nasal polyps…